Vol.52 No.5 May 2004
Annual change of susceptibility of Pseudomonas aeruginosa isolated from lower respiratory tract or urinary tract infections against antibacterial agents
1)Department of Microbiology, Toho University School of Medicine,
5-21-16 Omori-nishi, Ota-ku, Tokyo, Japan
2)Department of Laboratory Medicine, Toho University Omori Hospital
Abstract
The susceptibilities of Pseudomonas aeruginosa isolated from lower respiratory tract infections (2,067 strains) and urinary tract infections (1,454 strains) against various antibacterial agents were examined. The strains were clinically isolated between 1996 and 2003 at Toho University Omori Hospital. Susceptibility rates (SR) were calculated according to break point of National Committee for Clinical Laboratory Standards document. Against strains isolated from lower respiratory tract infections, the SR of amikacin was superior to other drugs and was more than 88%. The SR of ceftazidime was 57% in 1996, but it recently increased and reached 92% in 2003. The SR of imipenem gradually decreased and was 54% in 2003. The SR of ciprofloxacin trended to recover after 1997, but it dropped by 67% in 2003. Against strains isolated from urinary tract infections, the trends of SR were similar to those of lower respiratory tract infections.
Key word
MIC, Pseudomonas aeruginosa, lower respiratory tract infection, urinary tract infection, ceftazidime
Received
April 2, 2004
Accepted
April 30, 2004
Jpn. J. Chemother. 52 (5): 256-264, 2004
