Vol.63 No.3 May 2015

The issues of resistant organisms in the treatment of surgical site infections in colorectal surgery

Hiroki Ohge^1,4), Toshinori Hara²⁾, Norifumi Shigemoto^1,4), Yumiko Koba²⁾, Maki Furushimo²⁾, Rie Nagaoka²⁾, Makoto Onodera²⁾, Shizuo Kayama³⁾, Motoyuki Sugai³⁾ and Taijiro Sueda⁴⁾

¹⁾Department of Infectious Diseases, Hiroshima University Hospital, 1-2-3 Kasumi, Minami-ku, Hiroshima, Japan
²⁾Laboratory Division of Clinical Support, Hiroshima University Hospital
³⁾Department of Bacteriology, Graduate School of Biomedical Science, Hiroshima University
⁴⁾Department of Surgery, Graduate School of Biomedical Science, Hiroshima University

Abstract

For the prevention or treatment of surgical site infections in colorectal surgery, both intestinal aerobes and anaerobes should be considered. Recent reports have indicated the resistance rate has been increasing in the Bacteroides fragilis group. While clindamycin is no longer used as an anti-anaerobic drug, metronidazole is now available in Japan and is one of the treatment options for intra-abdominal infections. In aerobes, ESBL-producing bacteria are increasing. Surveillance of the incidence and susceptibility pattern are required to make appropriate choice of antimicrobial prophylaxis and treatment.

Key word

surgical site infection, colorectal surgery, anaerobe, antimicrobial resistance

Received

December 10, 2014

Accepted

January 6, 2015

Jpn. J. Chemother. 63 (3): 339-342, 2015