Vol.67 No.4 July 2019
Update on sepsis management
Emergency and Critical Care Medicine, St. Marianna University Hospital, 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa, Japan
Abstract
Sepsis, which represents an uncontrolled response to infection, leads to organ dysfunction. The major principles of management of sepsis are control of the infection source with the use of antibiotics and organ function support. Management at intensive care units has decreased the mortality rate from sepsis over the last two decades, however further improvement of sepsis management is expected with the new guidelines for sepsis. This article reviews the key elements of and recent advances in sepsis management.
Key word
septic shock, early recognition of sepsis, rapid response system, fluid resuscitation, post-intensive care syndrome
Received
September 28, 2018
Accepted
January 8, 2019
Jpn. J. Chemother. 67 (4): 438-445, 2019
