Vol.73 No.4 July 2025
Investigation of changes in the rate of post-bronchoscopy pneumonia after discontinuation of prophylactic antibiotics
1)Department of Hospital Pharmacy, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki, Nagasaki, Japan
2)Infection Control and Education Center, Nagasaki University Hospital
Abstract
Bronchoscopy is an essential medical procedure that is widely used for the diagnosis and treatment of various respiratory diseases. One of the complications of bronchoscopy is the development of pneumonia after the procedure. However, guidelines do not recommend antibiotic prophylaxis prior to bronchoscopy. At Nagasaki University Hospital, prophylactic antibiotic administration was removed from the 2017-revised-clinical path for bronchoscopy, in consultation with other clinical departments. We retrospectively compared the incidence of pneumonia before and after the revision of the clinical path. Pneumonia after bronchoscopy occurred in 4 patients (0.51%) before the clinical path revision and in 5 patients (0.75%) after the revision. After revision of the clinical path, prophylactic antibiotics were prescribed, at the discretion of the attending physicians for 119 patients and clavulanic acid/amoxicillin was the most commonly used. This investigation suggests that the incidence of post-bronchoscopy pneumonia did not increase after the revised clinical path was applied, and that doctors prescribed antibiotics at their discretion in individual patients. In conclusion, omission of prophylactic antibiotic administration from the clinical path for bronchoscopic examination may encourage proper use of antibiotics.
Key word
transbronchial lung biopsy, pneumonia, antimicrobial prophylaxis
Received
December 20, 2024
Accepted
March 17, 2025
Jpn. J. Chemother. 73 (4): 329-332, 2025
