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Abstract

Vol.53 No.10 October 2005

Antimicrobial susceptibility of Gram-negative bacillus causing late-onset neonatal bacteremia in a neonatal intensive care unit

Hiroshi Sakata

Department of Pediatrics, Asahikawa Kosei Hospital, 1-24 Asahikawa, Hokkaido, Japan

Abstract

Between 1998 and 2004, we studied the minimal inhibitory concentration (MICs) of 11 strains of Gram-negative bacilli isolated from blood in patients with late-onset neonatal bacteremia in a neonatal intensive care unit. Pathogenic organisms were 3 in Acinetobacter spp., 2 in Enterobacter cloacae, 2 in Ralstonia pickettii, and 1 each in Klebsiella pneumoniae, Burkholderia cepacia, Pseudomonas aeruginosa, and Proteus mirabilis.
The susceptibility of ciprofloxacin, imipenem, and meropenem to these organisms exceeded 80%. Ciprofloxacin was not susceptible to P. aeruginosa, and imipenem and meropenem were not susceptible to R. pickettii.

Key word

gram-negative bacilli, bacteremia, neonatal intensive care unit, susceptibility

Received

July 25, 2005

Accepted

September 7, 2005

Jpn. J. Chemother. 53 (10): 623-626, 2005