Vol.54 No.3 May 2006
Virucidal efficacy of povidone-iodine products against caliciviruses
1)Department of Veterinary Microbiology, Graduate School of Agricultural and Life Sciences,
The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, Japan
2)Meiji Seika Kaisha, Ltd.
Abstract
An in vitro study comparing the virucidal activity of povidone-iodine (PVP-I) products and other antiseptics, such as ethanol, benzethonium chloride and chlorhexidine gluconate, against feline as well as canine caliciviruses was performed. All PVP-I products (PVP-I solution, PVP-I gargle, PVP-I scrub, PVP-I palm and PVP-I throat spray) reduced the viral infectious titers below or near the detection limit within a reaction time of only 10 seconds. The potency of PVP-I against caliciviruses clearly exceeded that of any other of the tested antiseptics. These results suggest that PVP-I may be effective against noroviruses, which are classified in the family Calicivirdae.
Key word
anti-viral activity, calicivirus, povidone-iodine
Received
February 3, 2006
Accepted
March 16, 2006
Jpn. J. Chemother. 54 (3): 260-262, 2006
