Vol.59 No.5 September 2011
Problems with the quality of minimum inhibitory concentration (MIC) measurement
1)Eiken Chemical CO., LTD Science Promotion 2nd Department Market Corresponding Division Sales Management Office, 4-19-9 Taito, Taito-ku, Tokyo, Japan
2)Teikyo University Graduate School Medical Technology Doctoral & Master's Degree Programs
3)Eiken Chemical CO., LTD
Abstract
Recently, reports in the clinical literature based on the minimum inhibitory concentration(MIC) value have frequently appeared. However, it is possible that the numerical value of the MIC might vary to some degree depending on the factor used to measure it, so that a problem might arise when attempting to capture the MIC as an absolute digital numerical value. In the present study, the authors have examined the individual factors which might have an influence on, and analyze the changes made to, the MIC value.
Key word
MIC, drug-susceptibility, growth curve, quality control range
Received
July 29, 2011
Accepted
August 11, 2011
Jpn. J. Chemother. 59 (5): 460-468, 2011
