Vol.59 No.5 September 2011
Problems in the susceptibility tests for atypical pathogens, Legionella spp., Chlamydiaceae, Mycobacterium tuberculosis and fungi
1)Department of Microbiology, St. Marianna University, 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa, Japan
2)Department of Infection Control, St. Marianna University Hospital
Abstract
In vitro antimicrobial susceptibility tests, MICs determinations, can play an essential role in the clinical management of infectious diseases. Standard methods for measuring MICs and their break points were supplied by some organizations, e.g., Clinical and Laboratory Standards Institute and Japanese Society of Chemotherapy. Most of their standards were for general bacteria. The susceptibility tests for the atypical pathogens e.g., Legionella spp., Chlamydiaceae, Mycobacterium tuberculosis and fungi are generally more difficult than for general bacteria and some of them are very problematic. The major problems in the susceptibility tests for atypical pathogens are presented in this review.
Key word
drug-susceptibility, Legionella spp., Chlamydiaceae, Mycobacterium tuberculosis, fungus
Received
July 26, 2011
Accepted
August 3, 2011
Jpn. J. Chemother. 59 (5): 469-473, 2011
