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Abstract

Vol.62 No.5 September 2014

Management of systemic fungal infection in patients with hematological disorders

Yoshinobu Kanda

Division of Hematology, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma, Omiya-ku, Saitama, Japan

Abstract

Systemic fungal infection is a frequent complication in immunocompromised patients. In the management of this complication, it is important to understand the causes of the patient's compromised immune system (e.g., mucosal damage, neutropenia, steroid administration, and T-cell deficiency). This understanding enables physicians to predict susceptible pathogens. Based on this prediction, physicians can plan prophylaxis, examinations, and treatments of systemic fungal infection.

Key word

invasive fungal infection, hematological disorder, leukemia, neutropenia, hematopoietic stem cell transplantation

Received

June 3, 2014

Accepted

July 15, 2014

Jpn. J. Chemother. 62 (5): 605-612, 2014