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Abstract

Vol.67 No.3 May 2019

Current status of vaccine development and availability for international travelers

Atsuo Hamada

Traveller's Medical Center, Tokyo Medical University Hospital, 6-7-1 Nishishinjyuku, Shinjyuku-ku, Tokyo, Japan

Abstract

Many infectious diseases that pose risks for international travelers can now be prevented by vaccination. Vaccines have been developed against cholera, hepatitis A, hepatitis E, Japanese encephalitis, meningococcal diseases, rabies, tick-borne encephalitis, typhoid fever, and yellow fever and are available globally. However, the development of vaccines that are effective against malaria, Zika virus infection, and enterotoxigenic Escherichia coli infection is not yet complete. Moreover, although the first vaccine against dengue fever was developed in 2015, there is concern about the safety and efficacy of this vaccine. In this review article, the characteristics and uses of those vaccines that have already been developed for international travelers are introduced. The status of vaccines currently under development for international travelers is also explained.

Key word

vaccine, traveler, dengue fever, malaria, Zika virus infection

Received

September 14, 2018

Accepted

December 25, 2018

Jpn. J. Chemother. 67 (3): 355-367, 2019