Vol.67 No.4 July 2019
Side effects of antituberculous drugs and countermeasures
Respiratory Disease Center, Fukujuji Hospital, Japan Anti-Tuberculosis Association, 3-1-24 Matsuyama, Kiyose, Tokyo, Japan
Abstract
Many Japanese doctors do not yet have the experience of prescribing antituberculous drugs, as the incidence of Mycobacterium tuberculosis infection has decreased remarkably in developing countries. However, the incidence of nontuberculous mycobacterial diseases is increasing, and rifampicin and ethambutol are prescribed for patients with Mycobacterium avium complex disease. Furthermore, isoniazid and rifampicin are currently administered to patients with latent tuberculosis infection. As the number of foreigners with active tuberculosis is increasing, the incidence of M. tuberculosis may also increase again. Therefore, it is important for Japanese clinicians to understand the side effects of antituberculosis drugs.
The Japanese Society for Tuberculosis (JSTB) has published a statement on the treatment of tuberculosis and the side effects of antituberculous drugs. In this paper, we present countermeasures against the side effects of antituberculous drugs recommended by the JSTB.
Key word
tuberculosis, anti-tuberculous drugs, adverse effect
Received
August 29, 2018
Accepted
January 21, 2019
Jpn. J. Chemother. 67 (4): 452-456, 2019
