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Abstract

Vol.69 No.4 July 2021

Building a system for accepting COVID-19 cases by applying drug management at a cancer hospital

Tomomi Sano1, 2), Mika Shiotsuka1), Osamu Kobayashi1), Masakazu Yamaguchi2) and Satoshi Iwata1)

1)Department of Infection Control and Prevention, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo, Japan
2)Department of Pharmacy, National Cancer Center Hospital

Abstract

It was expected that the number of patients with COVID-19 requiring hospitalization would increase worldwide. In the context of the worsening pandemic, the Tokyo Metropolitan Government requested the National Cancer Center Hospital to accept patients with COVID-19. Upon acceptance of the request, six working groups (WGs), i.e., the administrative/medical cooperation group, COVID-19 medical care group, cancer medical care group, medical resource management group, staff work/health management group and infectious disease zoning group, were constituted at our cancer hospital. The objective was to provide appropriate medical care for both cancer patients and patients with COVID-19. A COVID-19-dedicated ward was set up with 23 beds for admission of moderate cases and 2 beds for severe cases. A COVID-19 medical care manual was prepared in collaboration with the COVID-19 treatment team and the infection control team. The Pharmacy Department devised a system by which the ward staff confirmed the drugs that the patients were taking and had brought with them at the time of admission to the COVID-19 ward. The Pharmaceutical Affairs Committee reviewed and approved "off-label use" and "limited patient-only use" of the therapeutic agents favipiravir and ciclesonide for COVID-19. In addition, since the treatment for COVID-19 was prescribed by doctors who were not infectious disease specialists, the pharmacists in the Pharmaceutical Information Section of the Pharmacy Department prepared a master list of drugs with information on each drug that could be prescribed to treat COVID-19, and established a drug-ordering system so that there were no errors in the prescription. We accepted patients with COVID-19 for the first time at our hospital in April 2020. We report that we have been able to provide appropriate treatment by applying the in-hospital drug supply system that had been established in the past for cancer treatment.

Key word

COVID-19, favipiravir, ciclesonide, compassionate use, hospital pharmacy

Received

December 1, 2020

Accepted

March 3, 2021

Jpn. J. Chemother. 69 (4): 329-333, 2021