Vol.71 No.6 November 2023
Validation of the usefulness of the Japan Surveillance for Infection Prevention and Healthcare Epidemiology (J-SIPHE) data and exploration of methods of evaluation in the survey of oral antibacterial agent use in outpatients
1)Department of Pharmacy, NTT Medical Center Tokyo, 5-9-22 Higashi-gotanda, Shinagawa-ku, Tokyo, Japan
2)Department of Infection Diseases, NTT Medical Center Tokyo
Abstract
The Japan Surveillance for Infection Prevention and Healthcare Epidemiology (J-SIPHE) System can be used to easily calculate the antibacterial agent use density and days of therapy as indicators of antibacterial agent use for hospitalized patients. While these parameters are used to monitor the use of antibacterial agents at each facility and compare it with that at other facilities, there are no established indicators of antibacterial agent use in outpatient settings. Therefore, in this study, deviations from the actual administered data were investigated to examine the validity of the J-SIPHE data to determine the status of outpatient oral antibacterial agent use. To validate the indicators, we compared the defined daily dose/1,000 outpatients/day (DOD), number of prescriptions, and number of patients prescribed antibacterial agents.
Differences between actual administered data and J-SIPHE data were compared. The differences of the values of drug using dose (g) between both methods were within 10% in 18 (81.8%) of 22 antibacterial agents, and DOD were within 10% in 19 (86.4%) of 22 antibacterial agents. A comparison of the annual changes in the DOD, number of prescriptions, and number of patients prescribed antibacterial agents showed different trends of the DOD.
The findings of this study suggest that the J-SIPHE application is a valuable tool to calculate the DOD for evaluating antibacterial agent use in the outpatient setting.
Key word
oral antibacterial agents, Japan Surveillance for Infection Prevention and Healthcare Epidemiology, outpatient
Received
April 19, 2023
Accepted
September 1, 2023
Jpn. J. Chemother. 71 (6): 576-581, 2023
